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Prevention traial of dementia using nonpharmacological interventions in Mild Cognitive Impairment (MCI) among the community-dwelling elderly

Prevention traial of dementia using nonpharmacological interventions in Mild Cognitive Impairment (MCI) among the community-dwelling elderly - Ajimu Project

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-C000000449
Enrollment
50
Registered
2006-07-15
Start date
2003-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment (MCI)

Interventions

Intervention group attend the occupational therapy and aerobic therapy once a week for three years. Non-intervention group attend a dementia enlightenment lectuer once a year and live ordinary life. C

Sponsors

Fifth Department of Internal Medicine, School of Medicine, Fukuoka University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The MCI subjects were selected from community-dwellers aged 65 years or above in Ajimu, Japan. The subject was defined as amnestic subtypes of MCI according to the criteria of the follows; insidious onset and gradual progression, impaired memory, the 32 words delayed recall score 1.0 SD below an education adjusted norm, a Clinical Dementia Rating (CDR) of 0.5, a score of 24 to 30 on the Mini-Mental State Examination (MMSE), and age of 65 years or above.

Exclusion criteria

Exclusion criteria: 1.Patients of (1)Ischemic heart disease (2)Dementia 2.Persons with mental problems 3.Pregnant women 4.Persons who are not adequate for the research

Design outcomes

Primary

MeasureTime frame
The subject is observed cognitive functions using "Five-Cog", a neuropsychological assessment comprised of five categories: memory, attention, verbal fluency, clock drawing test, and analogy. This examination is evaluated every one year.

Secondary

MeasureTime frame
Brain perfusion SPECT study, MMSE, CDR, WMS-R (logical memory I)

Countries

Japan

Contacts

Public ContactTatsuo Yamada

Fukuoka University Fifth Department of Internal Medicine

tyamada@fukuoka-u.ac.jp092-801-1011

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026