Patients with macular edema from branch retinal vein occlusion
Conditions
Interventions
Group1: grid laser photocoagulation
Group2: pars plana vitrectomy
Sponsors
Kagoshima University Graduate School of Medical and Dental Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants must have center-involved macular edema secondary to branch retinal vein occlusion documented for at least 2 months and not longer 18 months Visual acuity greater than or equal to 0.1 (logMAR1.0) and less than or equal to 0.5 (logMAR0.3) Foveal retinal thickness greater than or equal to 250 microns of the optical coherence tomography (mean of 2 measurements).
Exclusion criteria
Exclusion criteria: Ischemic maculopathy and macular degeneration Presence of hemorrhage directly in the fovea Additional ocular disease reducing the visual acuity Sitting systolic blood pressure greater than 180 mmHg or diastolic blood pressure greater than 110 mmHg at the screening visit History of systemic corticosteroids within 4 months prior to randomization History of laser photocoaguration for macular edema History of major ocular surgery within 6 months prior to randomization History of peribulbar or retrobulbar or intravitreal corticosteroid use History of pars plana vitrectomy Aphakia Pregnancy History of allergy to fluorescein uncontrollable systemic disease participation in another trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 12 months distant visual acuity 12 months foveal retinal thickness | — |
Secondary
| Measure | Time frame |
|---|---|
| Course of distant visual acuity over treatment period Course of foveal retinal thickness over treatment period Ischemic maculopathy at 12 months | — |
Countries
Japan
Contacts
Public ContactTaiji Sakamoto
Kagoshima University Graduate School of Medical and Dental Sciences Ophthalmology
Outcome results
None listed