Chronic heart failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) NYHA Classification class 2 or 3. 2) LVEF<=45% in UCG. 3) Patients who are stable for more than two weeks on NYHA Classification. 4) Patients with mild hypercholesteremia (T-Cho<=250mg/dL or LDL-Cho<=170mg/dL).
Exclusion criteria
Exclusion criteria: 1) Patients who had already treated with statin. 2)Patients who will undertake changes of alternative treatment of CHF. 3) Myocardial infarction occurred within three months. 4) CABG or PCI performed within three months, or planning them. 5) Patients with active malignant tumor. 6) Patients with severe renal and hepatic dysfunction. 7) Patients with collagen disease. 8) Pregnant, lactating, and probably pregnant patients, and patients who want to become pregnant during the study period. 9) Patients whose consent is not obtained from themselves in written form. 10) Other patients judged as being inappropriate for the subjects of the study by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac death or hospitalization due to worsening CHF. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total mortality Cardiac death Hospitalization due to worsening CHF Acute myocardial infarction or unstable angina pectoris Cerebral stroke Undergo percutaneous coronary intervention Surgical therapy for worsening CHF Composite of above | — |
Countries
Japan
Contacts
Chiba University Graduate School of Medicine Department of Cardiovascular Science and Medicine