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PEARL Study(PITAVASTATIN HEART FAILURE Study)

PEARL Study(PITAVASTATIN HEART FAILURE Study) - PEARL Study(PITAVASTATIN HEART FAILURE Study)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-C000000428
Enrollment
470
Registered
2006-06-09
Start date
2006-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic heart failure

Interventions

Sponsors

Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine
Lead Sponsor
Saga University Faculty of Medicine Department of Cardiovascular &amp
Collaborator
Renal Medicine and other institutes
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) NYHA Classification class 2 or 3. 2) LVEF<=45% in UCG. 3) Patients who are stable for more than two weeks on NYHA Classification. 4) Patients with mild hypercholesteremia (T-Cho<=250mg/dL or LDL-Cho<=170mg/dL).

Exclusion criteria

Exclusion criteria: 1) Patients who had already treated with statin. 2)Patients who will undertake changes of alternative treatment of CHF. 3) Myocardial infarction occurred within three months. 4) CABG or PCI performed within three months, or planning them. 5) Patients with active malignant tumor. 6) Patients with severe renal and hepatic dysfunction. 7) Patients with collagen disease. 8) Pregnant, lactating, and probably pregnant patients, and patients who want to become pregnant during the study period. 9) Patients whose consent is not obtained from themselves in written form. 10) Other patients judged as being inappropriate for the subjects of the study by investigators.

Design outcomes

Primary

MeasureTime frame
Cardiac death or hospitalization due to worsening CHF.

Secondary

MeasureTime frame
Total mortality Cardiac death Hospitalization due to worsening CHF Acute myocardial infarction or unstable angina pectoris Cerebral stroke Undergo percutaneous coronary intervention Surgical therapy for worsening CHF Composite of above

Countries

Japan

Contacts

Public ContactHiroyuki Takano

Chiba University Graduate School of Medicine Department of Cardiovascular Science and Medicine

pearl-admin@umin.ac.jp043-226-2701

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026