Comparison of efficacy and tolerability between transdermal fentanyl and oral oxycodone in patients with cancer pain

Comparison of efficacy and tolerability between transdermal fentanyl and oral oxycodone in patients with cancer pain - Comparison of efficacy and tolerability between transdermal fentanyl and oral oxycodone in patients with cancer pain

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-C000000339

Enrollment

Registered

2007-01-01

Start date

2006-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer pain

Interventions

Oral oxycodone-transdermal fentanyl

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients with cancer pain (2) A constant oral dose of oxycodone for two days or more, oral rescue morphine not over 45mg per day and VAS value not over 3 (3) A daily dose of oxycodone is 20 mg to 140 mg. (4) Patients recording pain score for a week or more (5) Patients with written consent

Exclusion criteria

Exclusion criteria: (1) patients with severe hepatic, renal, cardiocascular or pulmonary disease (2) patients with past history of heart or psychiatric disease (3) preganat or nursing patients and patients who may be pregnant (4) unconsciousness patient who cannot communicate (5) Patients who have contraindication to oral oxycodone and transdermal fentanyl (6) Patients taking fentanyl, extended-release morphine or opioid agonist-antagonists (7) A daily dose of oxycodone is not constant after agreement (8) Patients with a medical problem with this study

Design outcomes

Primary

Measure	Time frame
Evaluation of a conversion ratio of oral oxycodone to transdermal fentanyl	—

Secondary

Measure	Time frame
Comparison of side effects between oral oxycodone and transdermal fentanyl	—

Countries

Japan

Contacts

Public ContactMasahiro Kakuyama

Kyoto University Hospital Department of anesthesia

075-751-3435

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026