Randomized controlled trial to evaluate the effects of the surgical instrument LigaSure on reduction of time of liver transection time, compared with the conventional clamp crushing method at the single institution

Randomized controlled trial to evaluate the effects of the surgical instrument LigaSure on reduction of time of liver transection time, compared with the conventional clamp crushing method at the single institution - Randomized controlled trial to evaluate the effects of LigaSure concerning liver transection time

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-C000000337

Enrollment

120

Registered

2006-02-24

Start date

2006-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing liver resection.

Interventions

Liver transcetion using LigaSure Liver transection by the clamp crushing method

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients, who are 20-85 years old. scheduled to undergo hepatectomy at our institution, provide a written informed consent, and do not meet the below exclusion criteria.

Exclusion criteria

Exclusion criteria: 1.Simultaneous development of other malignant disease (except a colorectal carcinoma associated with liver metastasis) 2.Cases with high-risks of bleeding, for example; platele counts 5min., PT% < 50% 3.Cases in which inflow occulusion is impossible. 4.Cases with bilio-enteric reconstruction 5.Emergency operation case 6.Cases with some complications of heart, lung, and kidney.

Design outcomes

Primary

Measure	Time frame
Liver transection time in hepatectomy	—

Secondary

Measure	Time frame
Transection area per minute, total operation time, total amount of bleeding, amount of bleeding during transection, amount of transfusion, incidence of bile leakage, postoperative bleeding, incidence of pleural effusion/ascites, hospital stay, postoperative iver function, total bilirubin value of the drained discharge	—

Countries

Japan

Contacts

Public ContactMami Ikeda

University of Tokyo, Tokyo University Hospital Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery

ikemami-ind@umin.ac.jp03-5800-8654

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026