Evaluating safety and efficacy of low dose monteplase and nicorandil injected before percutaneous coronary intervention on left ventricular wall motion in patients of acute myocardial infarction:a randomized study.

Evaluating safety and efficacy of low dose monteplase and nicorandil injected before percutaneous coronary intervention on left ventricular wall motion in patients of acute myocardial infarction:a randomized study. - Injection of low dose monteplase and nicorandil before percutaneous coronary intervention in patients of acute myocardial infarction(SALMAN study).

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-C000000229

Enrollment

Registered

2005-09-14

Start date

1999-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction

Interventions

Both Monteplase,15000u per kg,and Nicorandil,4mg bolus injection and 96mg per day continuous injection,are injected. Monteplase but no Nicorandil are injected Nicorandil but no Monteplase are injecte

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Acute myocardial infarction within 12 hours from onset.

Exclusion criteria

Exclusion criteria: Severe hepatic or renal dysfunction,anemia,restricted to use Monteplase or Nicorandil and to treat by PCI.

Design outcomes

Primary

Measure	Time frame
Left ventricular wall motion,event of heart failure,death and re-infarction,bleeding complication,time to recanalization,angiographical data,serum CPK and CKMB	—

Secondary

Measure	Time frame
Restenosis of infarcted artery	—

Countries

Japan

Contacts

Public ContactIwao Ishibashi

Chiba Emergency Medical Center Division of Cardiology

rocky12qq@aol.com043-279-2211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026