Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) Study: Prospective Randomized Open-label Blinded Endpoint (PROBE)

Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) Study: Prospective Randomized Open-label Blinded Endpoint (PROBE) - HOMED-BP Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-C000000137

Enrollment

9000

Registered

2005-09-09

Start date

2001-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Untreated essential hypertensive patients

Interventions

Less intensive group (Home BP value 125/85-134/84 mmHg) and any angiotensin II receptor blockers as a first-line drug. Less intensive group (Home BP value 125/85-134/84 mmHg) and any angiotensin c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Home systolic BP value >= 135 and/ or diastolic BP >= 85 mmHg without antihypertensive medication.

Exclusion criteria

Exclusion criteria: Severe hypertension (either Home BP >= 180/120 mmHg or Clinic BP >= 220/125 mmHg), pure systolic hypertension (Home systolic BP >= 135 mmHg and Home diastolic BP =< 65 mmHg), pure diastolic hypertension (Home systolic BP =< 110 mmHg and Home diastolic BP >= 85 mmHg), or contra-indication to treatment with Ca-A, ACE-I, ARB.

Design outcomes

Primary

Measure	Time frame
The composite of non-fatal stroke, non-fatal myocardial infarction, and cardiovascular death.	—

Secondary

Measure	Time frame
Cerebrovascular disease, coronary heart disease, heart failure, renal failure, peripheral vascular disease, cancer, pneumonia, occurrence of new diabetes and mortality by all causes.	—

Countries

Japan

Contacts

Public ContactKei Asayama

HOMED-BP Secretariat Secretariat

homedbp@mail.tains.tohoku.ac.jp022-717-7775

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026