gastric neoplasm
Conditions
Interventions
A: Surgery:D2 dissection
B: Surgery:D2+paraaortic dissection
Sponsors
Japan Clinical Oncology Group(JCOG)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Preoperatively, (1) histologically proven adenocarcinoma (2) 75 years old or younger (3) forced expiratory volume in one second ≥ 50 % (4) arterial oxygen pressure in room air ≥ 70 mmHg (5) creatinine clearance ≥ 50 ml/min (6) written consent. Intraoperatively (7) mMacroscopic T staging is T2-subserosa, T3, or T4 (8) potentially curative operation is possible (9) no gross metastasis in para-aortic nodes (frozen section diagnosis not allowed) (10) peritoneal lavage cytology is negative for cancer cells
Exclusion criteria
Exclusion criteria: (1) Carcinoma in the remnant stomach (2) Borrmann type 4 (linitis plastica) (3) synchronous or metachronous malignancy in other organs except for cervical carcinoma in situ and colorectal focal cancer in adenoma (4) past history of myocardial infarction or positive results of exercise ECG (5) liver cirrhosis, or chronic liver disease with indocyanine green test ≥10%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival | — |
Secondary
| Measure | Time frame |
|---|---|
| relapse-free survival, operative morbidigy and mortality, length of postoperative hospital stay, quality of life | — |
Countries
Japan
Contacts
Public ContactMitsuru Sasako, MD
JCOG9501 Coordinating Office Gastric Surgery Division, National Cancer Center Hospital
Outcome results
None listed