Colorectal diseases in which elective colorectal resection is necessary
Conditions
Interventions
Single intravenous dose of 1 g cefmetazole just before skin incision,
Three-dose group given an intravenous dose of 1 g cefmetazole just before skin incision, and two postoperative 1-g doses at 8 and
Sponsors
National Cancer Center Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Colorectal diseases (cancer, large polyp, cacinoid, lymphoma,sarcoma and so on) in which elective colorectal resection is necessary
Exclusion criteria
Exclusion criteria: 1) Age < 20, 80 < Age 2) Emergent operation 3) Ileus 4) No resection 5) Preoperative infectious diseases 6) Penicillin or cephalosporin allergy 7) Antibiotics administration before surgery 8) Inflammatory bowel diseases 9) Angina or myocardial infarction 10) Renal dysfunction 11) Diabetes mellitus 12) Steroid administration before surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of incisional surgical site infection (SSI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidences of organ/space SSI and other infectious diseases. Other postoperative complications and postoperative hospital stay | — |
Countries
Japan
Contacts
Public ContactShin Fujita
National Cancer Center Hospital Colorectal Surgery Division
Outcome results
None listed