Malignant vena cava stenosis.
Conditions
Interventions
Metallic stents are placed in malignant vena cava stenosis using angiography technique.
Sponsors
Japan Interventional Radiology in Oncology Study Group(JIVROSG)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Symptomatic malignant vana cava stenosis in superior vena cava or inferior vena cava confirmed by contrast enhanced CT. 2) Uncontrolled symptom by medical treatment. 3) Adequate cardiac, hepatic, renal, respiratory, and bone marrow functions. 4) Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 3. 5) Expected survival more than 4 weeks. 6) Written informed consent.
Exclusion criteria
Exclusion criteria: 1) Potential benefit for symptom relief by chemotherapy, radiotherapy, or surgery. 2) Intraluminal tumor thrombus resulting in stenosis of vena cava. 3) Floating thrombus distal to stenosis. 4) Stenoses both in superior and inferior vena cava. 5) Central venous pressure higher than 8cm H2O. 6) Deformity of cardiac cavity, cardiac tamponade or severe functional disorder oberved by electrocardiogram and ultrasound examination. 7) Stenosis existinf both in SVC and IVC. 8) Active inflammatory disease. 9) Acute active bleeding. 10) Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of clinical symptoms | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events, improvement of findings on venography, techinical success rate. | — |
Countries
Japan
Contacts
Public ContactYasuaki Arai
JIVROSG, Coordinating Office Division of Diagnostic Radiology, National Cancer Center Hospital
Outcome results
None listed