Unresectable malignant lung tumor.
Conditions
Interventions
A radiofrequency needle is inserted into the lung tumor percutaneously, and then, radiofrequency tumor ablation is performed.
Sponsors
Japan Interventional Radiology in Oncology Study Group (JIVROSG)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Histologically confirmed malignant lung tumor. 2) Maximum diameter of the lesion on CT image between 1.0cm and 2.5cm. 3) No previous loco-regional therapy for the tumor. 4) Definitive accumulation of the tumor on FDG-PET study. 5) No vessel more than 5mm in diameter on the puncture route. 6) Adequate cardiac, hepatic, renal, respiratory, coagulation, and bone marrow functions. 7) Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2. 8) Expected survival more than 2 months. 9) Written informed consent.
Exclusion criteria
Exclusion criteria: 1) Unmeasurable lesion on CT. 2) Lesion with ground-glass opacity on CT. 3) Lesion adjacent to heart, mediastinum, pleura and vessel or bronchus more than 5mm in diameter. 4) Active inflammation or infection. 5) Fever above 38 degrees Celsius. 6) Cardiac pacemaker. 7) Anti-coagulant medication. 8) Severe dysfunction in the contra-lateral lung. 9) Pulmonary hypertension. 10) Difficulty of normal activity due to cerebrovascular disease, prior neurosurgery or trauma. 11) Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adverse events | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease of tumor accumulation on the image obtained by FDG-PET. | — |
Countries
Japan
Contacts
Public ContactYasuaki Arai
JIVROSG, Coordinating Office Division of Diagnostic Radiology, National Cancer Center Hospital
Outcome results
None listed