granulomatous mastitis
Conditions
Interventions
Post ulceration group:Puncture of breast lesions and Draw venous blood
Clinical healing group:Draw venous blood
Mass stage group:Puncture of breast lesions and Draw venous blood
Abscess stage group:Puncture of breast lesions and Draw venous blood
Health volunteer group: Draw venous blood
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria of GM patients (1) Female patients who meet the diagnostic criteria of traditional Chinese and western medicine and syndromes of GM and are diagnosed as GM by pathological biopsy. (2) Women older than 18 years. (3) No other basic diseases. (4) Volunteer to participate in clinical research and sign the informed consent form. Inclusion criteria for healthy volunteers (1) Women aged>18 years, matched with the age of patients with granulomatous mastitis. (2) No other basic diseases. (3) Volunteer to participate in clinical research and sign the informed consent form.
Exclusion criteria
Exclusion criteria: GM patient exclusion criteria (1) Patients with breast fibroma, breast cancer, breast hyperplasia and other breast tumors or breast diseases. (2) Patients with serious primary diseases, serious diseases that affect the survival of patients, or mentally and legally recognized disabled patients. (3) The patients in the clinical recovery period and the patients in the other three stages have intersected. Exclusion criteria for healthy volunteers (1) Health volunteers participating in other medical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Polynuclear giant cells, neutrophils, lymphocytes, plasma cells, microabscesses, granulomas;White blood cell count,Percentage of neutrophils,CRP,ESR,IL-8,IL-10,IL-22,IL-23,IL-33,PRL;TNF-a\CD68\CD163\CCL-5\IgG4 \TLR2\TLR4;Mycobacterium tuberculosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bacterial culture of secretions;Breast ultrasound;Breast pain; | — |
Countries
Chnia
Contacts
Public ContactYubo Guo
Outcome results
None listed