The clinical effect of compound Syndrome Differentiation with periodontal nonsurgical treatment on the Chronic Periodontitis

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2200006841

Enrollment

Unknown

Registered

2022-11-30

Start date

2022-12-01

Completion date

Unknown

Last updated

2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis

Interventions

Shenyinkuixu group:Zhibaidihuang

Weihuoshangzheng group:Qingweisan

Qixueliangkui group:Bazhentang

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1, Age from 18 to 65. 2, Patients got chronic periodontitis which according to periodontal classification in 1999. 3, Remind 16 teeth expect the third molar. 4, At last 2 sites PD=5 mm, CAL=2 mm, in different quardent. 5, CBCT show bone loss.

Exclusion criteria

Exclusion criteria: 1, Serious organ dysfunction. 2, Serious infectious diseases. 3, Mental illness or consciousness disorder. 4, Patients got periodontal treatment in last 6 months, took antibiotic, immunomodulator, glucocorticoid or sex hormone in last 3 months. 5, Oral therapy contraindication. 6, Allergy to our study's medicines. 7, Women in pergnancy or lactation period.

Design outcomes

Primary

Measure	Time frame
Probing depth;Bleeding index;Point table of Syndrome of traditional Chinese medical;	—

Secondary

Measure	Time frame
Reture visit period;TNF-a;Porphyromonas gingivalis;Alveolar bone loss;IL-1ß;IL-1;IL-6;Plaque index;	—

Countries

the People's Republic of China

Contacts

Public ContactGuangliang Niu

newgl@sina.com15801082159

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026