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Study on the mechanism of rapid effect of soothing liver and regulating mind acupuncture on mild depressive disorder based on emotional motivation and frontal lobe related brain network

Study on the mechanism of rapid effect of soothing liver and regulating mind acupuncture on mild depressive disorder based on emotional motivation and frontal lobe related brain network

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006824
Enrollment
Unknown
Registered
2022-11-25
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild depressive episode

Interventions

Acupuncture group:acupuncture

Sponsors

Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: (1) The first depressive episode, without systematic and standardized treatment, meets the ICD-10 diagnostic criteria for mild depressive episode; (2) 8 points = HAMD (Hamilton Compression Scale) - 17 points = 17 points; (3) The age ranged from 18 to 55 years; (4) Right handed; (5) Those who can understand and complete the contents of the observation indicators of this study and agree to sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Organic mental disorder, or depression related to psychoactive substances and non addictive substances; (2) Have other family psychiatric history, such as dementia, schizophrenia, mania, addiction, etc; (3) Pregnancy, preparation for pregnancy or lactation; (4) Patients with skin lesions or skin diseases, severe diabetes, tumors or serious cardiovascular, lung, liver, kidney, hematopoietic system and other medical diseases; (5) Those who have a history of self injuring behavior, suicidal tendency and attempted suicide (6) The daily mood measurement of this study could not be completed due to the reversal or irregularity of daily work and rest.

Design outcomes

Primary

MeasureTime frame
Emotional Motivation;Resting brain network index;Paradigm of Emotional Attention Bias;Hamilton Depression Scale-17 (HAMD-17);Beck depression rating scale (BDI-13);

Secondary

MeasureTime frame
the Difficulties in Emotion Regulation Scale (DERS);

Countries

China

Contacts

Public ContactWang Shanze

Guangdong Provincial Hospital of Traditional Chinese Medicine

wangshanze@gzucm.edu.cn18819300928

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026