Clozapine
Conditions
Interventions
Control group:take lactulose
Experimental group:Take Tiaoying Zengye Decoction
Sponsors
Shanghai jing'an mental health center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ?. According to the Diagnostic and Statistical Manual of Mental Diseases (the fifth edition), the patient is diagnosed as a mental disease; ?. Stable treatment of mental illness; ?. Meet the Rome IV diagnostic criteria for functional constipation; ?. Dialectics is yin deficiency; (5) Aged between 18 and 65; (6) Take clozapine treatment, and use it steadily for = 1 month (7) Be able to read and understand the informed consent form, voluntarily participate in the test and sign the informed consent form; (8) There are no serious diseases of the center of gravity, liver, kidney, hematopoietic system and other influences; (9) No use of prokinetic drugs, microecological agents and other drugs that significantly affect defecation
Exclusion criteria
Exclusion criteria: ?. Those who do not meet the inclusion criteria; ?. Unstable period of chronic somatic diseases; (3) Pregnant or lactating women; ?. Allergic system or allergy to multiple drugs; ?. Those who cannot use drugs as required, cannot judge the efficacy, or have incomplete data that affect the efficacy or safety judgment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Defecation situation;Patient Assessment of Constipation symptom (PAC-SYM); | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive and Negative Symptom Scale (PANSS);Treatment Emergent Symptom Scale (TESS); | — |
Countries
China
Contacts
Public Contactbaoyijie
Shanghai jing'an mental health center
Outcome results
None listed