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Clinical study on the treatment of male sterility after the failure of test-tube baby by Orange Nucleus Activating Essence prescription

Clinical study on the treatment of male sterility after the failure of test-tube baby by Orange Nucleus Activating Essence prescription

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006809
Enrollment
Unknown
Registered
2022-11-22
Start date
2022-11-30
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male infertility

Interventions

The control group:L-carnitine oral liquid
The treatment group:Ju He Huo Jing Decoation

Sponsors

Shenzhen Traditional Chinese Medicine Hospital(The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine)
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: ? Age 23-50 years old; ? Assisted reproduction failed once or more; ? TCM syndrome differentiation is kidney deficiency damp-heat syndrome; ? Normal sexual function; ? Informed consent was signed, and volunteers were included in the observation. The Western diagnostic criteria for male infertility, the diagnostic criteria for IVF failure and the TCM syndrome differentiation criteria for kidney deficiency and damp-heat can be referred to the research plan.

Exclusion criteria

Exclusion criteria: ? Spouses with serious gynecological diseases can not exclude the impact on fertility or diagnosed infertility diseases; ? Erectile dysfunction, abnormal ejaculation; (3) Taking anti-epilepsy, anti-tumor drugs that hinder spermatogenesis and sperm motility; Genital congenital malformation, seminal tract obstruction, testicular atrophy, etc.; (5) Combined with cardiovascular, liver, kidney and hematopoietic system and other serious primary diseases; ? Allergic constitution or allergic to the drug.

Design outcomes

Primary

MeasureTime frame
Positive rate of anti-sperm antibody;Sex hormone levels;Test tube success rate;Sperm DNA fragmentation rate;Seminal plasma biochemical;High quality embryo rate;Semen routine;Natural conception;TCM syndrome score;

Countries

China

Contacts

Public ContactHong zhiming
hzm001983@126.com13631699269

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026