perioperative neurocognitive disorders
Conditions
Interventions
Experimental group:Perioperative management and jing-well point health exercises
control group:Perioperative management
Sponsors
Shanghai Fourth People's Hospital affiliated to Tongji University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) Age 60 years and above; 2) Patients with an estimated anesthesia time of more than 2 hours for elective gastrointestinal surgery; 3) The patients or their families agree to join the study and singe the informed consent form of this study; 4) ASA class I-III.
Exclusion criteria
Exclusion criteria: 1) Patients with central nervous system diseases, including severe cerebrovascular diseases, dementia and mental diseases; 2) Patients with severe liver dysfunction (child Pugh grade C), severe renal insufficiency (dialysis), preoperative left ventricular ejection fraction less than 50%, sick sinus syndrome, severe sinus bradycardia (< 50 beats / min), secondary or greater atrioventricular conduction obstruction without pacemaker; 3)Long-term use of psychotropic drugs 4)History of drug and alcohol abuse (drinking more than 100ml of alcohol with over 40 degrees per day in the past three months) 5)People who have had multiple operationsPatients who had undergone cardiac surgery or craniocerebral surgery within 1 year; 6)Communication problems, such as severe impairment of hearing, vision or speech; 7)The operation lasted more than 3 hours and the intraoperative blood loss exceeded 800 ml; 8)The preoperative MMSE score was less than 24 points; 9)Patients who have participated in other relevant clinical studies within 3 months; 10)The same patient can only be included once, regardless of whether the reason of the second operation is related to the first cause.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment;Mini-mental State Examination;confusion assessment method; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hospital stay;CRP;Modified Barthel index;Incidence of postoperative complications; | — |
Countries
China
Contacts
Public ContactAn-Ren Zhang
Outcome results
None listed