COPD
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Aged 18-80 (including 18 and 80); ? Patients with severe chronic obstructive pulmonary disease (COPD) in group C meeting the diagnostic criteria; ? There is no acute exacerbation within 4 weeks (the patient is in the stable period, or the inpatients in the acute exacerbation period enter the stable period after standardized treatment); ? Sign the informed consent;
Exclusion criteria
Exclusion criteria: ? COPD patients with asthma, pulmonary tuberculosis, bronchiectasis, lung cancer and other patients who are not suitable for pulmonary rehabilitation; ? COPD patients with serious cardiovascular, cerebrovascular, liver, kidney, blood, endocrine and other major diseases; ? Patients with severe musculoskeletal diseases; ? There are metal foreign bodies within 30cm of the treatment site; ? Long term oxygen inhalation is required. Spontaneous pneumothorax or recurrent pneumothorax, giant pulmonary bullae and rib fracture have occurred in the past six months; ? High spinal cord injury, muscle disease; ? No drugs that affect nerve conduction and muscle contraction, such as vecuronium bromide, benzodiazepines and aminoglycosides, were used within one week.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function;Phrenic motor evoked potential;Blood gas analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| 6-minute walk distance measurement;MCSS score;CAT score;MMRC score; | — |
Countries
China