Chronic urticaria
Conditions
Interventions
control group:cetirizine hydrochloride
treatment group:Gubenkangmin prescription
Sponsors
Guangdong Provincial Hosptial of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the chronic spontaneous urticaria diagnosis creteria and urticaria activity score weekly(UAS7)=16; 2. Male and female aged 18 to 65 years old; 3. Patients with syndrome pattern of Wei qi deficiency; 4.To be able to and willing to provide signed informed consent.
Exclusion criteria
Exclusion criteria: (1)those with severe acute attack of urticaria , appearing with chest tightness, asthma, dyspnea,asphyxia or other life-threatening symptoms such as high fever, shivering, pulse speed and so on; (2)those who are pregnant ,lactating or prepared for pregnancy within the next six months ; (3)suffering from serious mental disorders; (4)suffering from other skin disorders which need treatment at the same time;or with severe primary diseases concerned about circulatory system, respiratory system, digestive system, urinary system, endocrine system ,hematopoietic system or with therioma, beyond the control of conventional treatment;or with obvious abnormal medical examination results:such as increase of alanine aminotransferase(ALT) or aspartate aminotransferase(AST)>treble the normal upper limit,increase of creatinine>treble the normal upper limit; (5)antihistamines or Chinese medicine were used within 1 week before entering the study, steroids hormone(oral medication),immunoglobulin, immunosuppressive drugs ,autohemotherapy were used within 4 weeks ,biologics and steroids hormone(injection) were used within 12 weeks; (6) allergy to drugs used in this study; (7) involved in other clinical studies at the same time or in the last 4 weeks. (8)people whose job require high concentration (9)Patients should not be enrolled according to the judgment of their physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| recurrent times;chronic urticaria quality of life questionnaire;recurrence interval;Urticaria Control Test (UCT);urticaria activity score weekly(UAS7); | — |
Countries
china
Contacts
Public ContactJie Guo
Outcome results
None listed