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A clinical study to evaluate the effect of Wei's Huoxue Tongluo Recipe in the treatment of ischemic optic neuropathy based on OCTA ocular blood flow dectection

A clinical study to evaluate the effect of Wei's Huoxue Tongluo Recipe in the treatment of ischemic optic neuropathy based on OCTA ocular blood flow dectection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006740
Enrollment
Unknown
Registered
2022-11-03
Start date
2022-11-07
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Ischemic Optic Neuropathy,AION

Interventions

Control group:Compound Anisodine Injection + Wei's Huoxue Tongluo Granule Mimic
Experimental group:Wei's Huoxue Tongluo Granules + Sterile Water for Injection

Sponsors

Dongfang Hospital, Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: ?Age between 40-80 years old; ? Meet the diagnostic criteria for ischemic optic neuropathy; ? Conform to the diagnosis of Qi deficiency and blood stasis type; ? The course of the disease is more than 3 months; ? intraocular pressure <21mmHg; ? Voluntarily participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: ? The onset eye cannot cooperate with the OCTA examination; ? Those who are allergic to the drugs studied in this group; ? Combined with mental disorders and serious organic diseases; ? Those who participate in other ophthalmic clinical trials; ? Those who have other organic eye diseases, such as glaucoma, uveitis, eye trauma, etc., and need urgent treatment; ? Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
best corrected visual acuity,BCVA;capillary perfusion density;

Secondary

MeasureTime frame
blood flow index;retinal nerve fiber layer thickness;TCM Syndrome Score;visual field;

Countries

CHINA

Contacts

Public ContactLiao Liang

Dongfang Hospital, Beijing University of Chinese Medicine

58273677@qq.com13466379490

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026