osteoporosis
Conditions
Interventions
control group:Oral calcium carbonate D3, calcitriol
Observation group:orally administered of Guilu Erxian Gum combined with calcium carbonate D3 tablets, calcitriol
Sponsors
Qingdao Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Comply with the diagnostic criteria of Western medicine and TCM for osteoporosis; 2. Male or female, age 50-85, female natural menopause for more than 1 year; 3. The patient signed the informed consent form, was willing to accept the examination and treatment, and was able to cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: (1) Various types of metabolic bone diseases, such as osteogenesis imperfecta, osteomalacia, Cushing's syndrome, hyperprolactinemia, thyroid or parathyroid diseases, etc; (2) Secondary osteoporosis, or disuse osteoporosis caused by limb deformity and disability; (3) Patients with other serious diseases, such as brain, heart, lung, liver, kidney and hematopoietic system; (4) Those who take drugs that affect bone metabolism or have received medical treatment for osteoporosis within 12 months; (5) Those who are allergic to the study drug;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-18;IL-1ß;NLRP3;Caspase-1;bone density;TCM clinical symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| renal function;Pain score;MDA;NO;liver function;Bone metabolism index; | — |
Countries
China
Contacts
Public ContactQi Shubin
Outcome results
None listed