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Study on the characteristics of damp-heat syndrome of calcium oxalate stones and its association with the molecular phenotype network of the gut-kidney axis

Study on the characteristics of damp-heat syndrome of calcium oxalate stones and its association with the molecular phenotype network of the gut-kidney axis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2200006712
Enrollment
Unknown
Registered
2022-10-26
Start date
2022-10-26
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Calcium Oxalate Stones

Interventions

healthy individuals group:null
calcium oxalate stones in the upper urinary tract with damp-heat syndrome group:null
calcium oxalate stones in the upper urinary tract with non-damp-heat syndrome group:null

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All subjects should meet the following conditions 1. Over 18 years old; 2. Without significant changes in diet and lifestyle habits in the recent period; 3. Subjects who voluntarily participate in the study and cooperate with relevant examination, treatment and evaluation; 4. Subjects who sign informed consent. Subjects in each group should also meet the following conditions 1. Calcium oxalate stones in the upper urinary tract with damp-heat syndrome group: (1) Patients meeting the diagnostic criteria of calcium oxalate stones in the upper urinary according to Chinese Urology and Andrology Disease Diagnosis and Treatment Guidelines(2019 version); (2) Patients with TCM syndromes of damp-heat based on Guidelines for Clinical Research of New Chinese Medicine Drugs 2. Calcium oxalate stones in the upper urinary tract with non-damp-heat syndrome group: (1) Patients meeting the diagnostic criteria of calcium oxalate stones in the upper urinary according to Chinese Urology and Andrology Disease Diagnosis and Treatment Guidelines(2019 version); (2) Patients with TCM syndromes not consistent with damp-heat 3. Healthy control group: Subjects had no history of urinary stones and imaging tests exclude the diagnostic criteria of urinary stone.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating women; 2. Patients with severe liver and kidney diseases (severe liver diseases refer to liver cirrhosis, portal hypertension and variceal bleeding, and severe kidney diseases include dialysis and kidney transplantation); 3. Patients with tumor; 4. Patients who are participating in other studies and affect the evaluator of this study.

Design outcomes

Primary

MeasureTime frame
TCM syndrome information;Stones related information;Biochemical indicator;Gut microbiota;

Countries

China

Contacts

Public ContactZhou Jianfu
zhoujianfu@gzucm.edu.cn+86 15915728725

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026