Calcium Oxalate Stones
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All subjects should meet the following conditions 1. Over 18 years old; 2. Without significant changes in diet and lifestyle habits in the recent period; 3. Subjects who voluntarily participate in the study and cooperate with relevant examination, treatment and evaluation; 4. Subjects who sign informed consent. Subjects in each group should also meet the following conditions 1. Calcium oxalate stones in the upper urinary tract with damp-heat syndrome group: (1) Patients meeting the diagnostic criteria of calcium oxalate stones in the upper urinary according to Chinese Urology and Andrology Disease Diagnosis and Treatment Guidelines(2019 version); (2) Patients with TCM syndromes of damp-heat based on Guidelines for Clinical Research of New Chinese Medicine Drugs 2. Calcium oxalate stones in the upper urinary tract with non-damp-heat syndrome group: (1) Patients meeting the diagnostic criteria of calcium oxalate stones in the upper urinary according to Chinese Urology and Andrology Disease Diagnosis and Treatment Guidelines(2019 version); (2) Patients with TCM syndromes not consistent with damp-heat 3. Healthy control group: Subjects had no history of urinary stones and imaging tests exclude the diagnostic criteria of urinary stone.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Patients with severe liver and kidney diseases (severe liver diseases refer to liver cirrhosis, portal hypertension and variceal bleeding, and severe kidney diseases include dialysis and kidney transplantation); 3. Patients with tumor; 4. Patients who are participating in other studies and affect the evaluator of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM syndrome information;Stones related information;Biochemical indicator;Gut microbiota; | — |
Countries
China