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Exploring the Optimal Diagnosis and Treatment Strategy of Traditional Chinese Medicine Preparation Sangqi Qingxuan Ointment For Prevention and Treatment of Prehypertension and Grade 1 Hypertension:Based on the Regulation of Autonomic Nerve Function

Exploring the Optimal Diagnosis and Treatment Strategy of Traditional Chinese Medicine Preparation Sangqi Qingxuan Ointment For Prevention and Treatment of Prehypertension and Grade 1 Hypertension:Based on the Regulation of Autonomic Nerve Function

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006668
Enrollment
Unknown
Registered
2022-09-29
Start date
2022-09-30
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

Chinese medicine group:Sangqi Qingxuan Ointment
Western medicine group:Losartan Potassium

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Understand the process of this trial, participate voluntarily and sign the informed consent 2. Meet the diagnostic criteria for primary hypertension grade 1 or prehypertension 3. In line with the TCM dialectical diagnosis of Yin deficiency of liver and kidney and/or hyperactivity of liver Yang and mutual junction of phlegm and blood stasis 4. No combined use of any western antihypertensive drugs 5. Age between 18 and 70

Exclusion criteria

Exclusion criteria: 1. Those who cannot cooperate 2. Patients with secondary hypertension 3. Abnormal liver function, ALT, AST is more than 2 times the upper limit of normal 4. Kidney damage, blood creatinine greater than 133mmol/L 5. Patients with severe chronic gastrointestinal diseases 6. Active myocarditis or pericarditis 7. Unstable angina within 2 weeks 8. Planned cardiac surgery 9. Patients with significant hematologic disorders 10. Allergic to the test drug 11. Psychiatric disorders, drug or other substance abuse 12. Stressful situations such as surgery and severe trauma 13. Lactating women and women who are pregnant or preparing for pregnancy in the near future

Design outcomes

Primary

MeasureTime frame
blood pressure;

Secondary

MeasureTime frame
blood pressure variability;heart rate variabiity;

Countries

China

Contacts

Public ContactLI LIN
lilinxcy@126.com18600285198

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026