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A randomized controlled clinical study of Tonglin Guben Recipe on CIRF outcome after soft endoscopy for renal calculi

A randomized controlled clinical study of Tonglin Guben Recipe on CIRF outcome after soft endoscopy for renal calculi

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006638
Enrollment
Unknown
Registered
2022-09-22
Start date
2022-09-22
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal calculus

Interventions

Blank control group :No intervention drugs were used after operation
experimental group:Tonglin Guben formula group + oral treatment of potassium sodium hydrogen citrate granule group
experimental group:Oral treatment of potassium sodium hydrogen citrate granule group

Sponsors

The Second Affiliated Hospital of Guangzhou University of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ? Patients aged 18-70 years with renal calculi diagnosed by CT before operation; ? Patients with ureteroscopic lithotripsy and indwelling double J tube after operation; ? The intraoperative lithotripsy was successful (the maximum residual stone fragment measured at 4mm of the exposed part of holmium laser during the operation was = 4 mm, no obvious ureteral perforation, mucosal exfoliation, kidney bladder injury, severe bleeding and other intraoperative complications were found during the operation, which met the success criteria of the operation), and the postoperative kub and abdominal (double kidney) CT confirmed that the maximum residual stone diameter was = 4 mm. ? Those who are willing to participate in this study and can actively cooperate with follow-up visits and complete clinical observation.

Exclusion criteria

Exclusion criteria: ? Patients with lower urinary tract obstruction; ? Patients with X - ray negative calculi were diagnosed before operation; ? Patients with ureteral perforation, mucosal exfoliation, kidney or bladder injury, severe bleeding and other complications during the operation; ? Pregnancy, lactation or 3 months of childbearing demand; ? Uremic patients, diabetes patients who have undergone renal transplantation and whose blood glucose can not be controlled, and patients with liver dysfunction (ALT or ast > twice the upper limit of normal); ? Patients with this disease were treated with lithotripsy drugs in the past week; ? Known hypersensitivity to test drug components; ? Patients with acute and chronic renal failure; ? Those who participate in other clinical researches within six months; ? The researcher thinks it is not suitable for the candidates.

Design outcomes

Primary

MeasureTime frame
Effective rate of treatment;Stone elimination;Stone discharge and time;

Countries

China

Contacts

Public ContactQianming Zou

The Second Affiliated Hospital of Guangzhou University of traditional Chinese Medicine

411568329@qq.com13430394690

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026