knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of western medicine and traditional Chinese medicine for knee osteoarthritis, and the joint space is obviously narrowed on the weight-bearing frontal X-ray film, which is in line with Kellgren and Lawrence imaging grades III and IV, and is in line with unilateral total knee arthroplasty ( TKA) standard; patients with indications for surgery and ineffective after non-surgical treatment, patients and their families who are willing to undergo surgery. (2) Aged 55-75 years old; (3) The patient has normal intelligence, no language barrier, willing to receive treatment, and can cooperate with the doctor to successfully complete the postoperative pain grading score; (4) The patient himself agrees and signs the consent form. effect, and its mechanism of effect in enhancing postoperative analgesic efficacy.
Exclusion criteria
Exclusion criteria: (1) Those who have a history of allergies to alcohol, morphine, non-steroidal anti-inflammatory drugs or local anesthetics; (2) Those who have used sedatives, opioids for a long time, a history of alcohol abuse, and drug addicts; (3) Postoperative patients Unstable vital signs, obvious high fever and chills, large fluctuations in blood pressure and heart rate; (4) Neurosis and psychiatric patients; (5) Postoperative prosthesis loosening, periprosthetic fracture, quadriceps tendon rupture, patellar tendon (6) Those who are prone to bleeding and have severe heart, lung and renal insufficiency; (7) Those who suffer from other rheumatism and metabolic diseases at the same time, such as gout, rheumatoid arthritis, Hemophilia, ankylosing spondylitis, etc; (8) Those with electromagnetic devices in the body, such as cardiac pacemakers; (9) Patients with purulent, non-specific knee joint infectious inflammation; (10) At the same time Traumatic synovitis, villonodular pigmented synovitis and other patients with knee joint synovium as the main lesion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale(VAS);Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Survival of life-12(SF-12);pain threshold;Pain Sensitization Assessment;Infrared thermal imaging;Opioid-related adverse reactions;Quadriceps motor unit potential duration and amplitude;ß-Endorphin(ß-EP);The dosage, frequency and time of use of drugs in the analgesic pump; | — |
Countries
China