Laryngopharyngeal Reflux Disease
Conditions
Interventions
Control group:Esomeprazole Magnesium Enteric-Coated Tablets
Treatment group:Esomeprazole Magnesium Enteric-Coated Tablets
Treatment group:Traditional Chinese medicine prescription of 'Restraining the Liver and Strengthening the Spleen'
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who match the diagnostic criteria of laryngopharyngeal reflux disease and TCM syndrome differentiation is liver and stomach disharmony. 2. Between 18 and 65 years old, male or female. 3. Patients should be informed consent, and volunteer to participate in the study. 4. Be able to complete relevant records such as case record form as required.
Exclusion criteria
Exclusion criteria: 1. After this outbreak, other Chinese or Western medicines have been used to treat laryngopharyngeal reflux disease. 2. Pregnant women. If pregnant women are found during the study, the study will be suspended. 3. Unable to fully cooperate with the test and investigator due to intellectual or behavioral impairment. 4. Patients who are easily lost to follow-up due to frequent changes in working environment. 5. Suspected history of alcohol, antibiotics, hormones and other drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reflux Symtom Index;Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal flora;Reflux Finding Score; | — |
Countries
China
Contacts
Public ContactWenyong Chen
Outcome results
None listed