Hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Untreated patients who meet the diagnostic criteria of Western medicine for essential hypertension; Or patients with grade 1-2 hypertension who have taken antihypertensive drugs but still have poor blood pressure control; (2) The syndrome differentiation of traditional Chinese medicine is hyperactivity of liver yang or phlegm and blood stasis syndrome; (3) Age 18 ~ 75 years old (including 18 and 75 years old), gender unlimited; (4) Understand and sign the informed consent form; Volunteer subjects and collaborators.
Exclusion criteria
Exclusion criteria: (1) Exclude patients with secondary hypertension and those with grade 3 hypertension; (2) Those who do not meet the TCM syndrome differentiation criteria of hyperactivity of liver yang or phlegm and blood stasis syndrome; (3) Those who are taking traditional Chinese medicine or proprietary Chinese medicine with the effect of calming the liver, resolving phlegm and removing blood stasis (4) Patients who are taking control drugs or angiotensin converting enzyme inhibitors (ACEI) to control blood pressure; (5) 6 people who are taking lithium, potassium preserving diuretics, potassium supplements, potassium containing salt substitutes or other drugs that can increase serum potassium levels (6) Lactating or pregnant women; (7) Patients with serious primary diseases such as cardiovascular, cerebrovascular, liver, kidney and hematopoietic system in acute stage or uncontrolled; (8) Allergic constitution, multiple drug allergy or known drug allergy to the test group and the control group; (9) Those who have poor compliance, such as mental diseases, cannot effectively follow the doctor's advice, and thus cannot complete the observation of symptoms and the determination of efficacy and safety during the trial; (10) Those who are participating or have just participated in other clinical trials within 3 months; (11) The researcher judged that it was not suitable to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (1) Grading and quantitative scoring of TCM related symptoms;Indicators of blood pressure variability: including occasional blood pressure measurement and 24-hour ambulatory blood pressure; | — |
Countries
China