Study on the after-effects of upper limb motor cortex excitability induced by electroacupuncture at different frequencies

Study on the after-effect of upper limb motor cortex excitability induced by electroacupuncture at different frequencies

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2200006600

Enrollment

Unknown

Registered

2022-09-13

Start date

2022-09-20

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

4:Subjects respectively received twice 30 min EA stimulus on LI4 in three days (with 48 h intervals).

3:Subjects respectively received twice 30 min EA stimulus on LI4 in two days (with 24 h intervals).

5:Subjects only received once 30min sham EA stimulus on LI4.

1:Subjects only received once 30min EA stimulus on LI4.

2:Subjects respectively received twice 30 min EA stimulus on LI4 in one day (with 6 h intervals).

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Healthy subjects, aged from 18 to 35; 2. Right handed subjects, regardless of gender; 3. Patients without neurological, mental and motor diseases in the past; 4. Subjects who have not received any peripheral stimulation (such as acupuncture, peripheral electrical stimulation, etc.) or central stimulation (such as rTMS, tDCS, etc.) in the past 3 months; 5. Subjects who are willing to accept electroacupuncture and have no history of acupuncture sickness; 6. Subjects who voluntarily participated in this study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with mental system diseases, such as schizophrenia, anxiety disorder, personality disorder, etc; 2. Patients with nervous system diseases, such as brain trauma, posterior cranial fossa disease, spasm, trigeminal neuralgia, Jackson epilepsy, spasm after facial paralysis, blepharospasm, cognitive impairment, speech disorder and dementia, etc; 3. Patients with history of severe hypertension, diabetes, malignant tumor, and other diseases of heart, liver, kidney and other organs; 4. Patients with metal residues (including denture, pacemaker, nerve stimulator, medical pump, etc.); 5. Subjects who were afraid of TMS and could not be stimulated by TMS for other reasons; 6. Subjects who are afraid of acupuncture or have adverse reactions to acupuncture; 7. Pregnant or lactating women.

Design outcomes

Primary

Measure	Time frame
Grooved Pegboard Test;Motor evoked potential;	—

Secondary

Measure	Time frame
Motor threshold;latent period;	—

Countries

China

Contacts

Public ContactJianhua Liu

jyhf08@sina.com+86 13729889452

Outcome results