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Clinical study of microwave ablation vs. microwave ablation +Traditional Chinese medicine in treatment of thyroid microcarcinoma with multiple benign nodules: a randomized controlled trial

Clinical study of microwave ablation vs. microwave ablation +Traditional Chinese medicine in treatment of thyroid microcarcinoma with multiple benign nodules: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006554
Enrollment
Unknown
Registered
2022-09-01
Start date
2022-09-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid microcarcinoma

Interventions

Group A:microwave ablation
Group B:microwave ablation+Traditional Chinese Medicien decoction

Sponsors

Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Age >18, <80. ? Patients diagnosed as papillary thyroid microcarcinoma by ultrasound and fine-needle aspiration biopsy, BRAF V600E(+). ? Patients without cervical radiation history. ? Patients with contraindications or refusing surgery; ? Patients who refused long-term active follow-up observation.

Exclusion criteria

Exclusion criteria: ? BRAF V600E (-). ? TERT (+). ? Patients with cervical lymph node or distant metastasis founded by ultrasound or CT. ? Patients suffering from other malignant diseases. ? Patients with severe coagulopathy. ? Patients cannot cooperate with the operation because of mental or physical problems. ? Patients or family members refuse to participate the research. ? Patients who are unable to understand and cooperate with the questionnaire.

Design outcomes

Primary

MeasureTime frame
Thyroid function;Metastasis rate;Recurrence rate;Volume growth of benign thryoid nodule;

Secondary

MeasureTime frame
Hepatorenal function;doctor and patient's satisfaction;Complication rate;

Countries

China

Contacts

Public ContactYi-feng Zhang
27763289@qq.com+86 13564843665

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026