thin endometrium of kidney deficiency and blood stasis type before habitual abortion pregnancy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Married female, 20 years old = age = 40 years old; 2. Body mass index (BMI) 18-26 (kg/m2) (including boundary value); 3. It meets the diagnostic criteria of recurrent abortion and follicular dysplasia in western medicine and the diagnostic criteria of spleen and kidney deficiency in traditional Chinese medicine; 4. Good compliance, willing to participate in and cooperate with researchers to complete the study; 5. The nature, significance, possible benefits, possible inconvenience and potential risks and discomfort of the trial have been understood in detail before the trial, and they have voluntarily participated in the clinical trial and signed a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the above diagnostic criteria; 2. Age 40 years old; 3. Body mass index (BMI) 26 (kg/m2); 4. Congenital malformations or organic diseases of reproductive organs, such as uterine mediastinum, residual horn uterus, ovarian cyst, etc., which affect follicular development and ovulation; 5. Hypothalamic and pituitary factors affect follicular development and ovulation; 6. Ovarian tissue damage caused by malignant tumors, radiation, surgery or inflammation damage to the ovary, affecting follicular development and ovulation; 7. Have serious cardiovascular, liver, kidney and systemic diseases; 8. Vague consciousness and unable to accurately express discomfort symptoms; 9. Those who are known to be allergic to the study drug (including the excipients of the study drug) or its analogues, or those with allergic constitution (such as those who are allergic to two or more drugs, food and pollen); 10. Patients with sensitive skin, skin allergy, acute / chronic urticaria and other skin diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM clinical symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Endometrial thickness;Endometrial typing;Endometrial blood flow parameters (uterine artery PI, RI, s/d); | — |
Countries
China