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Effectiveness of Transcutanclus electrical acupoint stimulation combined with acupoint application on radiation-induced xerostomia in patients with oral cancer

Effect of Transcutanclus electrical acupoint stimulation combined with acupoint application on Radiation-Induced Xerostomia Among Patients With oral cancer: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006467
Enrollment
Unknown
Registered
2022-08-13
Start date
2022-08-13
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral cancer

Interventions

Experimental group:transcutaneous electrical acupoint stimulation Combined Application
Blank control group:Routine Care

Sponsors

Shanghai Ninth People's Hospital, Affiliated to Shanghai Jiaotong University, School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Oral cancer with radiation and histological confirmation.Adult > 18 years of age, without tumor recurrence. 2. with an anticipated survival of more than six months and Karnofsky performance status = 60. 3. Able to give informed consent and ethics committee approval. Patients communicate normally and (verbally or in writing). 4. Planned intensity-modulated radiation therapy (IMRT), with or without concurrent chemotherapy or induction treatment, no parotid duct ligation or excision, and best attempts to minimize the bilateral parotid. One parotid gland receives an average dosage of less than 20 Gy, while both parotid glands get an average dose of less than 25 Gy.

Exclusion criteria

Exclusion criteria: 1. History of xerostomia prior to head and neck radiation therapy, Sj?gren's disease, salivary fistula, or another underlying systemic illness is known to cause xerostomia. 2. Patients who do not want to participate in this experiment or those who receive therapy using a different approach and are unable to follow the prescribed course of treatment 3. History of communication disorders, psychiatric disorders, epilepsy, and cardiovascular disease. with a cardiac pacemaker. pregnant women. 4. lower extremity disorders that prevent the selection of acupuncture points and allergies to acupuncture point patches. 5. If a patient was using any salivary substitute, they were asked to refrain from using the product for at least 24 hours prior to saliva and questionnaire data collection. 6. currently taking amifostine, cholinergic agonist medications (pilocarpine, cevimeline), or other medications are known to affect salivary function.

Design outcomes

Primary

MeasureTime frame
Xerostomia Questionnaire(XQ);

Secondary

MeasureTime frame
salivary flow rate;QLQH&N35;

Countries

China

Contacts

Public Contactlili hou

Shanghai Ninth People's Hospital, Affiliated to Shanghai Jiaotong University, School of Medicine

Pisces_liz@163.com13816033620

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026