abnormal glucose metabolism and hypertension
Conditions
Interventions
control group:Losartan potassium + Yiqi Shengjin powder simulant
treatment group: Losartan potassium + Yiqi Shengjin powder
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) The subject or responsible guardian shall sign the informed consent; 2) Aged 18-75 years; 3) In patients with impaired fasting glucose, abnormal glucose tolerance or type 2 diabetes mellitus(HbA1C<8% in the past 2 weeks without taking or taking western antidiabetic drugs); 4) Patients with grade 1-2 essential hypertension; 5) TCM syndromes accord with Qi and Yin deficiency syndrome
Exclusion criteria
Exclusion criteria: 1) Pregnant and lactation patients; 2) Malignant tumors or blood diseases; 3) Patients who are critically ill or not yet stable in the acute phase, have consciousness disorders, severe cognitive dysfunction or serious mental diseases; 4) A history of alcohol and drug abuse; 5) Patients with acute myocardial infarction, unstable angina pectoris, large aneurysm or dissecting aneurysm, NYHA class III-IV heart failure, malignant arrhythmia, and other severe liver, kidney, hematologic, cerebrovascular diseases and severe osteoporosis within 6 months (Note: Liver dysfunction is to point to alanine aminotransferase or aspartate aminotransferase value is greater than 2 times the upper limit of normal; Renal insufficiency refers to a serum creatinine value greater than 2 times the upper limit of normal);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total effective rate of lowering blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxidative stress index;Lipid metabolism index;24h ambulatory blood pressure monitoring index;Glucose metabolism index;Vascular injury detection index;TCM syndrome integration;Aging indicators; | — |
Countries
China
Contacts
Public ContactHaoyue Shi
Outcome results
None listed