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Exploring the therapeutic mechanism of Batuanjin in the treatment of elderly stable angina pectoris based on gut microbiota - lipid metabolism spectrum

Exploring the therapeutic mechanism of Batuanjin in the treatment of elderly stable angina pectoris based on gut microbiota - lipid metabolism spectrum

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006443
Enrollment
Unknown
Registered
2022-08-08
Start date
2022-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stable angina pectoris

Interventions

Control Group:On the basis of basic treatment and health education, cooperate with free exercise. The main mode of exercise is 3~6mets (medium intensity) free exercise, and the exercise frequency is n
Baduanjin Group:On the basis of basic treatment and health education, cooperate with Baduanjin exercise. The main exercise mode is 3~6mets (medium intensity) Qigong Baduanjin exercise, the exercise fr

Sponsors

Guang'anmen Hospital of Chinese Academy of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) meet the diagnostic criteria of stable angina pectoris published by Chinese Medical Association in 2018 "guidelines for diagnosis and treatment of chronic stable angina Pectoris". (2) between 60 and 80 years old. (3) patients with severe angina pectoris classified as I~III by Canadian Cardiovascular Association (CCS). (4) those who sign the informed consent form. Those who have the above four items at the same time are included in the scope of the test.

Exclusion criteria

Exclusion criteria: (1) severe arrhythmia and moderate cardiac insufficiency (EF < 40%) (2) Hypertension is more than 180/100mmHg (3) patients with AMI history or percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG), severe trauma and cerebrovascular accident in recent 3 months. (4) patients with severe shock and severe primary organ diseases such as liver, kidney and lung. (5) patients with obvious infection, fever and severe anemia. (6) severe joint disease, which is not suitable for those who exercise eight-paragraph jingle. (7) use antibiotics or participate in any probiotics or laxatives research in the 3 months prior to the study.(8) There were no gastrointestinal diseases such as diarrhea and ulcerative colitis in the past two months.

Design outcomes

Primary

MeasureTime frame
total effective rate of angina pectoris symptoms;

Secondary

MeasureTime frame
changes of trimethylamine oxide;Changes of non-targeted lipid metabolism;Serum hypersensitive C-reactive protein;Seattle angina grading;Changes in gut microbial composition;Dosage;Quality of Life Questionnaire(SF-36);The TCM syndrome scores;Duration;Electrocardiogram;blood lipid levels;Attack frequency;Stopping rate of nitroglycerin;

Countries

China

Contacts

Public ContactWu Min

Guang'anmen Hospital of Chinese Academy of traditional Chinese Medicine

wumin19762000@126.com13671206090

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026