Diminished ovarian reserve
Conditions
Interventions
control group:sham acupuncture
experimental group:acupuncture
Sponsors
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) aged between 20-40; (2) meet the diagnostic criteria of DOR; (3) have a need for fertility, and intend to have a spontaneous pregnancy or to use an antagonist regimen to promote ovulation in the next IVF cycle evaluated by a reproductive physician; (4) volunteer to participate in the trial and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) combined with any kind of related diseases that affect conception like congenital developmental abnormalities of reproductive organs, untreated endometrial polyps, untreated uterine infection, etc; (2) combined with polycystic ovarian syndrome (PCOS); (3) combined with untreated hyperprolactinemia, hyperandrogenemia, abnormal thyroid function, chronic adrenal hypofunction, and other metabolic endocrine diseases; (4) combined with severe cardiovascular, cerebrovascular, liver, kidney, malignant tumors, hematopoietic system, and mental diseases; (5) have received acupuncture treatment related to improving fertility in the past three months; (6) expect to receive IVF-ET within 2 months after enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antral Follicle Count; | — |
Secondary
| Measure | Time frame |
|---|---|
| E2 level on HCG day;Number and rate of 2PN;High-quality embryo rate;Live birth rate;Intima thickness on HCG day;Continuous pregnancy rate;Available embryo rate;Biochemical pregnancy rate;Embryo implantation rate;MII oocytes;SAS score;Level of FSH;Cycle cancellation rate;Level of AMH;Number of follicles = 14mm;Clinical pregnancy rate;Early pregnancy loss rate; | — |
Countries
China
Contacts
Public ContactYigong Fang
Outcome results
None listed