Diminished ovarian reserve
Conditions
Interventions
case series:Nil
Sponsors
Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of DOR; (2) 18 years = age < 40 years. (3) Voluntary participation and informed consent.
Exclusion criteria
Exclusion criteria: (1) Polycystic ovary syndrome, hyperprolactinemia, hyperandrogenemia, hypothyroidism and other endocrine diseases affect ovulation; (2) DOR caused by iatrogenic factors (such as pelvic surgery, radiotherapy and chemotherapy, uterine artery embolization, drugs such as hormones, immunosuppressants, etc.); (3) Have taken hormone drugs (such as contraceptives, glucocorticoids, etc.) in the past three months (except those required for in vitro fertilization-embryo transfer); (4) Patients with severe anxiety with a Self-Rating Anxiety Scale(SAS) score > 70; (5) Combined with serious cardiovascular, cerebrovascular, liver, kidney, malignant tumor, hematopoietic system and mental diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical prenancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Embryo implantation rate;Available embryo rate;Uterine artery blood flow resistance index (RI);Endometrial volume;Menstrual volume;Live birth rate;Basal serum level of FSH;Basal serum level of FSH/LH;Endometrial thickness;AMH;Endometrial morphology;Uterine artery blood flow pulsation index (PI);SAS score;Endometrial vascularization flow index (VFI);Early pregnancy loss rate;Basal serum level of LH;Endometrial vascularization index (VI);AFC;Continuous pregnancy rate;Biochemical pregnancy rate;Basal serum level of E2;High-quality embryo rate;Menstrual duration;Endometrial flow index (FI);Number of eggs harvested;Menstrual cycle; | — |
Countries
China
Contacts
Public ContactHuanfang Xu
Outcome results
None listed