wet age-related macular degeneration
Conditions
Interventions
TCM Group:TCM combined with anti-VEGF treatment
Placebo Group:Placebo combined with anti-VEGF treatment
Sponsors
Shanghai Eye Disease Prevention and Treatment Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Any one eye meets the western diagnostic criteria of wet AMD; 2) Age =50; 3) Intravitreal injection of anti-VEGF drugs is required 4) The refractive stroma is basically clear, fundus examination and fundus OCTA are feasible; 5) Patients had good compliance with the observation and efficacy evaluation of the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1) The refractive medium is not clear enough to conduct fundus observer. 2) Combined with glaucoma, uveitis, severe cataract, vitreous hematocele, fundus vein obstruction, optic neuritis, retinal detachment and other ophthalmic diseases affecting vision or effect observation. 3) Patients who have received fundus surgery and laser treatment 4) Patients who had received intravitreal drug injection in last 3 months 5) complicated with other organs (such as heart, brain, liver) and other serious diseases, or mental patients. 6) Women who are pregnant, trying to become pregnant or breastfeeding. 7) Severe allergy to fluorescein sodium and indocyanqing green needles.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| best corrected visual acuity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean thickness of central macular area;Time/ratio of the fourth anti-VEGF treatment;retinal sensitivity;perfusion density of superficial retinal in macular;Choroidal neovascularization area;area of choroidal neovascularization;fixation characteristics;FAZ;Chinese medicine symptom complex score; | — |
Countries
China
Contacts
Public ContactHuang Jiannan
Outcome results
None listed