Idiopathic Membranous Nephropathy (IMN)
Conditions
Interventions
Control group:placebo, standard immunosuppressive and basic treatment.
Sanqi qushi granule Group:Sanqi qushi granule, standard immunosuppressive treatment and basic treatment.
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age = 14 years old. (2) Patients with determined diagnosis of IMN and need immunosuppressive therapy according to 2012 KDIGO guildlines; (3) Patients agree to paticipate in this study and sign on the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Secondary membranous nephropathy, i.e., caused by hepatitis B, SLE, malignancy, etc.; (2) A known of contraindications and/or hypersensitivity to any ingredients of our research medications; (3) Participating in another interventional clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| complete remission rate;partial remission rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| dampness syndrome score;concentration of PLA2R antibody;24-hour urine total protein;Urine Protein:Creatinine Ratio;estimated Glomerular Filtration Rate;side effect of immunology agents;endpoint events rate; | — |
Countries
China
Contacts
Public ContactKun Bao
Outcome results
None listed