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Clinical observation of Qingyi granule combined with dexamethasone in the treatment of acute pancreatitis

Clinical observation of Qingyi granule combined with dexamethasone in the treatment of acute pancreatitis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2200006356
Enrollment
Unknown
Registered
2022-07-11
Start date
2022-07-12
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute pancreatitis associated lung injury

Interventions

Conventional treatment+Qingyi Granules and Dexamethasone group:Nil
Conventional treatment and Qingyi Granules group:Nil

Sponsors

The First Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1)Acute pancreatitis patients who meet the diagnostic criteria for Atlanta; (2)Moderately severe acute pancreatitis (MSAP)or severe acute pancreatitis (Severe acute pancreatitis, SAP)patients, who meet one of the following three items is sufficient: (i)Acute Physiology and Chronic Health Assessment Form (APACHE-?)> 8 points(see attached table1); (ii)Ranson score> 3 points(see attached table2); (iii)Modified Marshall score = 2 points(see attached table3)(3)Age> 18 years old;

Exclusion criteria

Exclusion criteria: (1)Patients with severe heart, liver, and kidney diseases; (2)Patients with shock and cachexia; (3)Patients with recurrent acute pancreatitis; (4)Patients with previous hematopoietic system primary disease; (5)Patients with previous complications of rheumatic immune diseases or mental illness; (6)Pregnancy and puerperium; (7)Incomplete medical records;

Design outcomes

Primary

MeasureTime frame
mortality rate;Incidence of ALI/ARDS;Incidence of pleural effusion;

Secondary

MeasureTime frame
Laboratory indicators:Amy\Lps\Tbil\ALT/AST\?-GT\ALP\WBC\Urea\CRE\Ca2+;Incidence of abnormal bowel sounds;Duration of abdominal pain and bloating after admission;ICU occupancy rate;Ventilator utilization;

Countries

China

Contacts

Public ContactHailong Chen

The First Affiliated Hospital of Dalian Medical University

hailongchen2007@hotmail.com13304265752

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026