Uremia Hemodialysis
Conditions
Interventions
B:Contral
A:oral administration of Shenshuaining
Sponsors
Putuo Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) diagnosed with ESRD and treated with MHD;(2) Aged from 18 to 75 years old;(3) complied with hemodialysis treatment =3months;(4) not combinedly treated with PD; (5) not treated with intestinal detoxification drugs in recently one month were enrolled.
Exclusion criteria
Exclusion criteria: (1) Active stage or active infection of chronic systemic autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.); (2) Lactating women or planning to be pregnant;(3) Patients who need to take antibiotics or probiotics for a long time;(4) Patients who are allergic to SSN or other reasons;(5) Patients with cognitive impairment and psychosis;(6) Combined with advanced malignant tumor;(7) Patients who need to change hemodialysis prescription;(8) patients who researchers refuse to enroll
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bristol Score;indoxyl sulfate;Blood uric acid;Kynurenic acid;L-kynurenine;4-hydroxyhippuric acid;Hemoglobin;Indole-3-acetic acid;Melatonin;Blood urea nitroge;Serum creatinine;Hippuric acid;Number of bowel movements (times/week); | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum phosphorus;25-hydroxyvitamin D;The elf inhibition C;Kt/V;High-density lipoprotein;C-reactive protein;Serum calcium;Triglycerides;Parathyroid hormone;URR;Total cholesterol;Serum albumin;Low density lipoprotein; | — |
Countries
China
Contacts
Public ContactBai Tianli
Putuo Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed