Sepsis
Conditions
Interventions
controlled group:stroke-physiological saline solution
experimental group :Shenfu injection
Sponsors
Zhongnan Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria for sepsis (sepsis 3.0) 2.Age: 18-75 years old
Exclusion criteria
Exclusion criteria: 1.Expected ICU stay is less than 24 hours 2.Diagnosed with sepsis for more than 24 hours 3.Diagnosed with obstructive shock 4.Cardiogenic shock caused by acute myocardial infarction, valvular heart disease, dilated cardiomyopathy, restrictive cardiomyopathy, etc 5.History of CPR or advanced malignant tumor 6.Allergy history of Shenfu injection 7.Pregnant or breastfeeding women 8.Severe liver and kidney damage, requiring blood purification during the study 9.Use of immunomodulators or organ transplantation within 6 months 10.Participated in other clinical trials in the past three months 11.Use of other traditional Chinese medicines during the study 12.Other special circumstances are excluded by the clinical staff at the time of registration 13.If a patient misdiagnosed with sepsis is identified, he/she should be removed after enrollment Patients with the following conditions will be withdrawn:(1)leaving the ICU without authorization;(2)incomplete follow-up;(3)poor compliance. Document the reasons for the patient's withdrawal from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality; | — |
Countries
China
Contacts
Public ContactBo Hu
Outcome results
None listed