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Effects of Jianpi Lushi Jiedu Formula on postoperative recurrence of colorectal adenoma with spleen deficiency and dampness syndrome and its mechanism based on IL-6/JAK/STAT3 signaling pathway

Effects of Jianpi Lushi Jiedu Formula on postoperative recurrence of colorectal adenoma with spleen deficiency and dampness syndrome and its mechanism based on IL-6/JAK/STAT3 signaling pathway

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006127
Enrollment
Unknown
Registered
2022-06-14
Start date
2022-06-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal adenoma

Interventions

control group:Not taking medicine

Sponsors

Nanjing Hospital of Integrated Traditional Chinese and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) The colorectal polyp was diagnosed by colonoscopy. The histopathologic examination was consistent with adenoma, and the adenoma had been excised or resected by endoscopy,in addition to treatment, and TCM syndrome in line with the spleen-deficiency syndrome of damp-toxin patients; 2) Age from 18 to 75, male or female; 3) The patients gave full informed consent and accepted the observation completely voluntarily, and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1) It does not accord with the diagnostic standard of colorectal polyp or the diagnostic standard of TCM syndrome of adenoma or damp-toxin syndrome of spleen deficiency by pathology; 2) A pregnant or lactating woman or a person preparing to give birth; 3) Allergic constitution or allergic to many kinds of drugs; 4) Patients with severe heart, lung, liver, kidney and blood system diseases; 5) The patients with suspicious canceration or canceration have been examined by biopsy; 6) Patients who took the drug or were in another clinical trial within 1 month.

Design outcomes

Primary

MeasureTime frame
Recurrence rate of colorectal adenoma;

Secondary

MeasureTime frame
An indicator of inflammatory cytokines;Protein expression index of colon tissue;Protein expression index of colon tissue;

Countries

china

Contacts

Public ContactLIU Wanli

Nanjing Hospital of Integrated Traditional Chinese and Western Medicine

18951768998@163.com18502506688

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026