Idiopathic Membranous Nephropathy
Conditions
Interventions
blood stasis:Qilong Tongshen Granules
humid stasis type:Fenqinghuazhuo capsules
Sponsors
Shanxi Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ( 1 ) Patients with idiopathic membranous nephropathy ( IMN ) nephrotic syndrome confirmed by renal biopsy and clinical examination were pathologically divided into stages I to II ; ( 2 ) Age in 18-75 years old, gender, ethnic limit ; ( 3 ) signing informed consent ; ( 4 ) TCM syndromes are qi deficiency and blood stasis or damp heat and blood stasis ; ( 4 ) 24-hour urinary protein excretion > 3.5g / 24h ( 5 ) Serum creatinine = 133umol / L or endogenous creatinine clearance rate 60ml / min / 1.73m2 was included in the study.
Exclusion criteria
Exclusion criteria: ( 1 ) Pregnancy or lactation patients ; ( 2 ) Complicated with severe primary diseases such as decompensated cirrhosis, active malignant tumor or hematopoietic system ; ( 3 ) Those with acute myocardial infarction, cerebral infarction or cerebral hemorrhage in the first three months were included ; ( 4 ) Severe arrhythmia, severe heart failure, NYHA class III or above ; ( 5 ) Patients with severe infectious diseases when included ; ( 6 ) Patients with clear thrombosis were included ; ( 7 ) During the treatment period, the patients with natural loss or loss of follow-up, poor compliance and discontinued or not taking medicine, there are serious adverse events, serious other patients with onset or deterioration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma albumin;24 hours urinary protein excretion; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood total cholesterol;serum creatinine;blood urea nitrogen;triglyceride;low density lipoprotein;urine routine;high density lipoprotein; | — |
Countries
China
Contacts
Public ContactWang shi rong
Outcome results
None listed