non-alcoholic steatohepatitis
Conditions
Interventions
treatment group:Huatan Qushi Huoxue granule
control group:placebo
Sponsors
The First Affiliated Hospital of Henan University of CM
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age: 18 to 65 years old, regardless of gender. (2) Meeting both Chinese and Western medical diagnostic criteria. (3) 1 times the upper limit of normal < serum ALT decreased = 3 times the upper limit of normal for more than 4 weeks. (4) Fasting blood glucose = 7.0 mmol/L. (5) Signed informed consent. (6) Not taking other drugs for the treatment of NAFLD or who have discontinued other drugs for the treatment of NASH before 4 weeks of inclusion for observation.
Exclusion criteria
Exclusion criteria: (1) viral hepatitis, drug-related liver disease, total parenteral nutrition, hepatomegaly, autoimmune liver disease, etc. (2) Those suffering from serious heart, brain, kidney, hematopoietic system diseases and emotional diseases such as anxiety, depression and psychiatric disorders. (3) Fatty liver caused by long-term use of glucocorticoids, chlorpromazine, insulin, etc. (4) Patients with type I diabetes mellitus. (5) Patients with various types of malignant tumors or those with previous history of malignant tumors (6) Pregnant and lactating women. (7) Those who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMI;CAP value of controlled attenuation parameter of transient elastic imaging of liver;ALT\AST; | — |
Secondary
| Measure | Time frame |
|---|---|
| FINS;HOMA-IR;FFA;BFR;TG\TC\HDL-C\LDL-C;WHR;FPG; | — |
Countries
China
Contacts
Public ContactZhao Wenxia
Outcome results
None listed