decline in ovarian reserve
Conditions
Interventions
Experimental group:Moxibustion combined with Western medicine
Sponsors
Nanjing Hospital of Traditional Chinese Medicine affiliated to Nanjing University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) It conforms to the above diagnostic criteria and dialectical classification of low ovarian reserve function of Traditional Chinese and western medicine and belongs to kidney deficiency and blood stasis type; (2) Women of childbearing age between 18 and 40; (3) No contraindications of hormone therapy; (4) No obvious pathological changes of heart, liver, kidney and other organs. ; (5) The male reproductive function is normal; (6) agree to receive treatment according to this protocol and follow up the observer; (7) Willing to sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Women who were in pregnancy or menopause at the time of visit. (2) Allergic to drugs and moxibustion. (3) Patients with congenital dysplasia of reproductive organs are confirmed to have organic diseases and secretory diseases that seriously affect menstruation, ovulation and fertility by conventional gynecological examination such as imaging examination and secretion examination. (4) Patients with malignant tumors of reproductive organs undergoing surgical treatment and mental illness. (5) They have received relevant treatment and may affect the effect indicators. (6) Patients voluntarily withdraw from treatment due to personal reasons. (7) The failure to strictly implement the intervention measures and change the treatment plan leads to the failure to collect or produce errors in the relevant data such as efficacy feedback and effect indicators. (8) Serious adverse reactions and complications occur during treatment, and patients cannot continue to receive treatment. (9) Drugs that interfere with the treatment plan were used during treatment. (10) Participate in other experimenters at the same time. (11) Unable to fill in various scales. (12) Do not want to be randomly grouped. (13) Severe heart, liver and kidney injury affects normal drug metabolism. (14) combined with other physiological or pathological conditions that may affect the effect indicators. Note: Patients who meet any of the above criteria are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mature follicle;Number of sinus follicles;Endometrial thickness;FSH (Follicle stimulating hormone);AMH (Anti-Mullerian hormone);LH (luteinizing hormone);E2 (estradiol);Oxidative stress index detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Self-rating Anxiety Scale;Perimenopausal symptom Scale;Ovulation rate;TCM clinical symptom score;The pregnancy rate; | — |
Countries
China
Contacts
Public ContactZhang Cairong
Outcome results
None listed