Stable Angina Pectoris
Conditions
Interventions
Control group :Western medicine routine treatment + Jiuxin pill placebo
Treatment group :Western medicine routine treatment + Jiuxin pill
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1.age from 35 to 74 (including boundary value), gender is not limited; 2.Conform to the western medicine diagnostic criteria for stable angina pectoris of coronary heart disease; 3.The history of stable angina pectoris shall not be less than 2 months; 4.The average number of angina pectoris attacks per week= 1 in the first month before being selected; 5.Canadian Cardiovascular Society (CCS) angina pectoris classification is grade II - III; 6.Sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with myocardial infarction in recent 3 months; 2.Patients who have received PCI or other cardiac surgery (such as CABG) in the past 1 year; 3.Patients who plan to undergo coronary revascularization (CABG or PCI) within 2 months; 4.Patients with unstable angina pectoris, intractable heart failure, cardiogenic shock, severe heart valve disease and other serious cardiovascular diseases; 5.Patients with poorly controlled hypertension (systolic blood pressure = 160mmHg or diastolic blood pressure = 100mmHg after treatment); 6.Patients with severe respiratory diseases such as severe pulmonary insufficiency; 7.Patients with severe liver and kidney diseases such as liver dysfunction (alanine aminotransferase or aspartate aminotransferase levels more than 2 times higher than the normal value), renal dysfunction (creatinine level is more than 2 times higher than the normal value); 8.Patients with malignant tumor, severe anemia, severe renal artery stenosis and other serious diseases or conditions; 9.Patients with contraindications to exercise treadmill test; 10.Patients who have participated in other clinical studies in the past 2 months; 11.Patients who are allergy to known ingredients of the study drug; 12.Women with positive pregnancy test, planned pregnancy or lactation; 13.Patients who could not participate in the study due to recent infection, trauma and other reasons considered by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seattle Angina Questionnaire (SAQ) Score;Treadmill Exercise Test: Total Exercise Time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Borg Perceived Exertion After Exercise;Treadmill Exercise Test: Metabolic Equivalent;Scoring of Four Diagnostic Information of Traditional Chinese Medicine;Treadmill Exercise Test: Maximum ST Segment Depression;Usage of Nitroglycerin, Drug Withdrawal and Reduction Rate;Treadmill Exercise Test: 1-minute Heart Rate Recovery;Average Number of Angina Attacks Per Week;Incidence of Major Adverse Cardiovascular Events; | — |
Countries
China
Contacts
Public ContactMao Jingyuan
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed