Polycystic ovary syndrome
Conditions
Interventions
PCOS acupuncture+IVF group:acupuncture+IVF
Healthy control group:IVF
PCOS IVF group:IVF
Sponsors
Chengdu Xinan Gynecological Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 35 Years
Inclusion criteria
Inclusion criteria: PCOS participants: (1)Meet the diagnostic criteria of PCOS and have induced anovulation or tried pregnancy after ovulation but have not been pregnant for more than 6 months; (2)Patients who met the indications of IVF and were determined by reproductive doctors to use GnRH antagonist protocol for IVF; (3)21=age=35; (4)Did not receive acupuncture treatment in the last 3 months; (5)Not participating in other ongoing clinical studies; (6)Patients signed informed consent to participate in the study voluntarily. Healthy participants: (1) 21 = age =35; (2) The chief complaint has no obvious discomfort; (3) Patients who met IVF indications only due to male factors; (4) No symptoms of primary dysmenorrhea occurred within 1 year before the study; (5) The results of laboratory examination and scale evaluation are within the normal range; (6) Not participating in other ongoing clinical studies; (7) Patients signed informed consent to participate in the study voluntarily.
Exclusion criteria
Exclusion criteria: PCOS participants: (1) Suffering from other diseases that affect fertility; (2) Clearly diagnosed autoimmune disease or pre-thrombotic state; (3) Suffering from uncured endocrine diseases; (4) Progressive or psychiatric diseases with definite diagnosis of serious primary or secondary diseases of internal medicine or surgery; (5) IVF patients who selected other protocols except GnRH antagonist protocol; (6) Those who took antibiotics in the last three months; (7) Patients with a history of gastrointestinal surgery; (8) Patients with inflammatory bowel disease, irritable bowel syndrome, autoimmune diseases, cancer or other diseases that may affect the intestinal flora; (9) Patients with uncontrollable diseases that cause inflammation; (10) Those who have taken beneficial bacteria within one month. Healthy participants: (1) Those who took antibiotics in the last three months; (2) Those who have received acupuncture treatment in the last three months; (3) Patients with a history of gastrointestinal surgery; (4) Patients with inflammatory bowel disease, irritable bowel syndrome, autoimmune diseases, cancer or other diseases that may affect the intestinal flora; (5) Patients with uncontrollable diseases that cause inflammation; (6) Those with a history of taking beneficial bacteria within one month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High quality embryo rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| APOB;Available embryo rate;LH;Blastocyst formation rate;LDL-C;Adverse event;TG;T;E;Number of available high quality embryos;BMI;Number of available embryos;P;HOMA-IR;Normal fertilization rate;APOA1;PRL;TC;FSH;HDL-C;WHR; | — |
Countries
China
Contacts
Public ContactJie Yang
Outcome results
None listed