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Study for the impact of acupuncture for the rate of high-quality embryos in PCOS patients undergoing IVF

Study on the Mechanism of Acupuncture to Improve Oocyte Maturation Rate in PCOS Patients Undergoing IVF via the Energy Metabolism Pathway of "Gut Microbiota-Pyruvate-Mitochondria" Axis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2200006088
Enrollment
Unknown
Registered
2022-06-10
Start date
2022-05-27
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

Acupuncture + IVF group:Acupuncture
IVF group:No acupuncture

Sponsors

Chengdu Xinan Gynecological Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
21 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1)Those who meet the diagnostic criteria of PCOS and have induced anovulation or have attempted pregnancy without pregnancy for more than 6 months after ovulation; (2)Patients who met the indications of IVF and were determined by reproductive doctors to GnRH antagonist protocol for IVF; (3)21 = age =35; (4)Did not receive acupuncture treatment in the last 3 months; (5)Not participating in other ongoing clinical studies; (6)Patients signed informed consent to participate in the study voluntarily.

Exclusion criteria

Exclusion criteria: (1)Suffering from other diseases affecting fertility; (2)Having a clearly diagnosed autoimmune disease or prethrombotic state; (3)Suffering from uncured endocrine diseases; (4)Suffering from definite diagnosis of internal and surgical serious primary or secondary diseases, progressive or mental diseases; (5)Those who choose other protocols except GnRH antagonist protocol for IVF; (6)Patients with bleeding tendency and prone to infection, or patients with severe allergies, or patients with skin ulcers, scars and other which will influence acupuncture operation.

Design outcomes

Primary

MeasureTime frame
High quality embryo rate;

Secondary

MeasureTime frame
Days of Gn;Biochemical pregnancy rate;Embryo implantation rate;Gn dosage;Multiple pregnancy rate;Live birth rate;SDS depression scale;Cause of cycle cancellation;Early miscarrige rate;F-G score;Ongoing pregnancy rate;Rosenfield score;SAS anxiety scale;Adverse events;Ectopic pregnancy rate;OHSS;MPCOSQ scale scores;Clinical pregnancy rate;

Countries

China

Contacts

Public ContactJie Yang
jenny_yang_jie@126.com13882296714

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026