Chemotherapy-induced nausea and vomiting of breast cancer
Conditions
Interventions
Experimental group:Conventional western medicine Wenzhong Jiangni San acupoint applicationand
Blank control group:Conventional western medicine placebo acupoint applicationand
Sponsors
The first affiliated hospital of Henan University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Breast cancer was diagnosed by pathological examination; (2) Patients with indications for chemotherapy who intend to undergo chemotherapy with AC; (3)The patients were 18-75 years old, had no vital organ dysfunction, and had an ECOG-PS score of 0-2; (4) Estimated survival time > 6 months; (5) Approved by the ethics committee, informed and voluntary to accept treatment, signed chemotherapy consent and informed consent.
Exclusion criteria
Exclusion criteria: (1) Those who do not meet the criteria for inclusion; (2) Vomiting from other causes prior to chemotherapy; (3) Have mental illness; (4) Patients and their family members do not agree to participate in this study, do not sign informed consent, poor compliance, cannot cooperate to complete this study; (5) Patients who also participated in other clinical research topics; (6) Patients with severe allergies to the study drugs (TCM, placebo, acupoint dressing, and 5-HT3RA); (7) Pregnant or lactation patients; (8) Change the chemotherapy regimen due to the progression of the disease during chemotherapy; (9) Patients who received any antiemetic medication in the 24 hours prior to chemotherapy; (10) Other circumstances that the project team deems necessary to exclude.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vomiting;nausea; | — |
Secondary
| Measure | Time frame |
|---|---|
| ECOG-PS grade;TCM syndrome integral;Visual analogue scale;The time from chemotherapy to the first rescue treatment;Number of rescue treatments; | — |
Countries
China
Contacts
Public ContactCheng Xu-feng
Outcome results
None listed