knee osteoarthritis
Conditions
Interventions
Control Group:(Sulfuric acid or hydrochloric acid) glucosamine
Treatment Group:Gubi recipe
Sponsors
Jiangsu Province Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for knee osteoarthritis; 2. Meet the criteria of TCM syndrome diagnosis of kidney deficiency and collateral obstruction syndrome; 3.50 years = age =75 years, no gender limitation; 4. Visual Analogue Scale (VAS) score of knee pain: 2 =VAS=6; 5. Knee osteoarthritis Kellgren&Lawrence grade =?; 6. Patients voluntarily participated in the study, read and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Other osteoarthritis patients, such as hip osteoarthritis, hand osteoarthritis, etc.; 2. Patients with secondary knee osteoarthritis caused by other diseases, such as joint trauma, congenital or genetic diseases, etc. 3. Patients with some serious primary diseases, such as digestive, respiratory, cardiovascular, hematopoietic and nervous system diseases, mental diseases, etc.; 4. Abnormal liver and kidney function, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) exceeding 1.5 times the normal value, blood creatinine (Scr) and urea nitrogen (BUN) any higher than the normal value; 5. Patients who had received knee arthrocentesis during recent 6 months; 6. Allergic constitution and allergic to clinical study medication; 7. Women who are during pregnancy, preparing for pregnancy, or during breastfeeding period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster University Osteoarthritis Index score; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome integral;Lequesne;VAS; | — |
Countries
China
Contacts
Public ContactLiang Fang
Jiangsu Province Hospital of Chinese Medicine
Outcome results
None listed