chronic obstructive pulmonary disease
Conditions
Interventions
Test group:Gubenquyujiedu granules
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients with AECOPD with grade I or II disease. (2) Patients with TCM evidence of stasis and toxin blockage. (3) The number of acute exacerbations of COPD in the past two years > 1 time/year. (4) 20 years old = age = 80 years old. (5) Voluntarily accept the treatment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with combined asthma, impaired consciousness, pneumonia, tuberculosis, pleural effusion, malignancy and hematological disorders. (2) Patients with severe impairment of cardiac, hepatic and renal functions (cardiac function grade 3-4, ALT and/or AST more than 1.5 times the upper limit of normal, Cr more than the upper limit of normal). (3) Suffering from mental illness, cardiovascular and cerebrovascular thrombotic diseases. (4) Persons with congenital or acquired immunodeficiency. (5) Those with known allergy to therapeutic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HIF-1a;VEGF;BODE Score;miRNA-199a-5p;miRNA-1-3p;6MWT;Blood gas analysis;Lung function;CAT Questionnaire;Quantitative scoring of TCM evidence;IL-8; | — |
Countries
China
Contacts
Public ContactZhang Wenjiang
Xi Yuan Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed